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Chemical Synthetic Biology: Deciphering and Engineering the Biosynthetic Pathways of Natural Products
2017-10-23 | 编辑: | 【 】| | 供稿部门:
    

Lecture: 

Chemical Synthetic Biology: Deciphering and Engineering the Biosynthetic Pathways of Natural Products 

Lecturer: 

Prof. Yeo Joon Yoon 

Time: 

9am, October 25, 2017, Wednesday   

Location: 

111 Meeting Room, Energy Building   

Introduction of Lecturer:   

Yeo Joon Yoon是韩国梨花女子大学化学与纳米科学学院教授。研究的主要方向:通过异源表达、组合式生物合成以及代谢工程等方法高效合成结构多样性的天然产物。在生物合成领域的研究具有很深的造诣,迄今Yeo Joon Yoon教授在PNASJACSNPRNat. Chem. Biol.等杂志发表学术论文120余篇。目前担任J. Microbiol. Biotechn.Appl. Microbiol. Biot.Biomed Res. Int.杂志编委,NPR杂志顾问委员会委员。 

Abstract: 

We are mainly working on characterization of the biosynthetic pathway and creating the structural diversity of natural products including polyketides and aminoglycosides through the combinatorial biosynthetic approach. Synthetic biology is a new area of biological research that combines science and engineering in order to design and build novel biological functions and systems. Combinatorial biosynthesis is one area of synthetic biology as well as chemical biology for the generation of novel natural products. The basic concept of combinatorial biosynthesis is combining metabolic pathways in different organisms on a genetic level. The synthetic biological approaches combined with combinatorial biosynthesis will allow us “the total biosynthesis of natural products”, which will eventually lead to the unlimited structural diversification of natural product, drug discovery, and mass production. Some recent examples for this chemical synthetic biology approaches will be presented. 

 
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